| Place | Performance | Athlete | Team |
| 1 | 21.97 | Q: ADAMS - KEENAN | EASTERN PROVINCE ATHLETICS |
| 2 | 22.05 | Q: NDLOVU - DENZEL | ATHLETICS GAUTENG NORTH |
| 3 | 22.24 | Q: MAKHAZA - SIBONGAKONKE | KWAZULU-NATAL ATHLETICS |
| 4 | 22.27 | q: DE VILLERS - LIAM | ATHLETICS GAUTENG NORTH |
| 5 | 23.65 | -: KLAASTE - ANWHA | NORTHWESTERN CAPE ATHLETICS |
| 6 | 24.38 | -: BOTHMA - BRANDON-LEIGH | WESTERN PROVINCE ATHLETICS |