| Place | Performance | Athlete | Team | Wind |
| 1 | 11.74 | Q: CROUS - QAADIRAH | WESTERN PROVINCE ATHLETICS | -0.7 |
| 2 | 11.71 | Q: KOTZE - AMY | ATHLETICS FREE STATE | +0.3 |
| 3 | 11.21 | Q: DAVIS - CHRYSTABEL | ATHLETICS GAUTENG NORTH | +0.4 |
| 4 | 11.20 | Q: THEUNISSEN - MIGNON | CENTRAL GAUTENG ATHLETICS | +0.0 |
| 5 | 11.15 | Q: DE KLERK - HEIKE | ATHLETICS GAUTENG NORTH | -1.1 |
| 6 | 11.14 | Q: VAN BREDA - TAYLON | ATHLETICS VAAL TRIANGLE | -0.2 |
| 7 | 11.05 | Q: VAN DEN BERG - ALTEA | ATHLETICS GAUTENG NORTH | +0.0 |
| 8 | 11.04 | Q: DE VRIES - GRACE | BOLAND ATHLETICS | -0.5 |
| 9 | 10.74 | Q: VERMAAK - MIA | EASTERN PROVINCE ATHLETICS | +0.1 |
| 10 | 10.61 | Q: BADENHORST - AMORE | ATHLETICS GAUTENG NORTH | +0.2 |
| 10 | 10.61 | Q: NSOVO - NTLEMO | ATHLETICS GAUTENG NORTH | +0.1 |
| 10 | 10.61 | Q: KROMHOUT - MIEKE | ATHLETICS CENTRAL NORTHWEST | +0.0 |
| 13 | 10.53 | -: BAYISA - OLWETHU | ATHLETICS MPUMALANGA | -0.2 |
| 14 | 10.51 | -: BROWNE - HANEL | ATHLETICS FREE STATE | -0.3 |
| 15 | 10.50 | -: VAN ZYL - LIANE | ATHLETICS MPUMALANGA | +0.9 |
| 16 | 10.32 | -: MOKWENA - TSHEPI | ATHLETICS MPUMALANGA | +0.5 |
| 17 | 10.26 | -: COETZER - TERA-LEIGH | CENTRAL GAUTENG ATHLETICS | +0.4 |
| 18 | 10.21 | -: BOSHOFF - INGE | CENTRAL GAUTENG ATHLETICS | +0.0 |
| 18 | 10.21 | -: HILL - SUNE | ATHLETICS FREE STATE | +0.1 |
| 20 | 10.14 | -: MOGAJANE - CARMENITTAH | CENTRAL GAUTENG ATHLETICS | +0.1 |
| 21 | 09.70 | -: KLAASEN - KYLIE | EASTERN PROVINCE ATHLETICS | +0.1 |