| Place | Performance | Athlete | Team |
| 1 | 04:51.67 | Q: DU PLESSIS - LU-MARIE | ATHLETICS MPUMALANGA |
| 2 | 04:51.81 | Q: ROOME - MEGAN | CENTRAL GAUTENG ATHLETICS |
| 3 | 04:51.99 | Q: VAN ROOYEN - KAITLYN | ATHLETICS GAUTENG NORTH |
| 4 | 04:52.13 | Q: BLIGNAUT - ANNARI | ATHLETICS FREE STATE |
| 5 | 04:52.23 | Q: GUNTHER - ANKE | ATHLETICS FREE STATE |
| 6 | 04:52.47 | Q: LIEBENBERG - MATHILDA | ATHLETICS CENTRAL NORTHWEST |
| 7 | 04:54.03 | Q: FOURIE - KARA | EASTERN PROVINCE ATHLETICS |
| 8 | 05:00.20 | -: SITHOLE - SHEBA | ATHLETICS MPUMALANGA |
| 9 | 05:06.44 | -: SCHENK - LEILA | BORDER ATHLETICS |