| Place | Performance | Athlete | Team |
| 1 | 11.90 | Q: BURGER - RUM | ATHLETICS FREE STATE |
| 2 | 11.91 | Q: ROCHA - SELENA | ATHLETICS GAUTENG NORTH |
| 3 | 12.02 | Q: VAN OUDTSHOORN - KAYLIE | CENTRAL GAUTENG ATHLETICS |
| 4 | 12.09 | q: CILLIERS - ZO | ATHLETICS MPUMALANGA |
| 5 | 12.29 | -: MGQIBELA - BUHLE | ATHLETICS GAUTENG NORTH |
| 6 | 12.37 | -: MAKASI - LOLWETHU | CENTRAL GAUTENG ATHLETICS |
| 7 | 12.44 | -: VAN ROOYEN - KATHLEEN | ATHLETICS GAUTENG NORTH |
| 8 | 12.51 | -: MAREE - KYLA (KYLA - MAE) | ATHLETICS CENTRAL NORTHWEST |