| Place | Performance | Athlete | Team |
| 1 | 11.73 | Q: MARIAS - GABRIELLA | ATHLETICS FREE STATE |
| 2 | 11.73 | Q: LA GRANGE - KAYLA | CENTRAL GAUTENG ATHLETICS |
| 3 | 11.86 | Q: LE ROUX - KAYLEE | CENTRAL GAUTENG ATHLETICS |
| 4 | 12.02 | q: GEORGE - ANNESTAYSHA | ATHLETICS GAUTENG NORTH |
| 5 | 12.13 | q: OOSTHUIZEN - SYDNEY | ATHLETICS CENTRAL NORTHWEST |
| 6 | 12.31 | -: VLOK - KAYLA | ATHLETICS CENTRAL NORTHWEST |
| 7 | 12.40 | -: RHODE (WPIND) - CHELSEA ANN | WESTERN PROVINCE ATHLETICS |
| 8 | 12.50 | -: KEYS - ALECIA | WESTERN PROVINCE ATHLETICS |