| Place | Performance | Athlete | Team |
| 1 | 11.46 | Q: SIMPSON - JADEN | CENTRAL GAUTENG ATHLETICS |
| 2 | 11.51 | Q: KRUGER - RUBEN | CENTRAL GAUTENG ATHLETICS |
| 3 | 11.67 | Q: RHODES - COBYN | EASTERN PROVINCE ATHLETICS |
| 4 | 11.79 | -: MITCHELL - DARIANO | ATHLETICS GRIQUALAND WEST |
| 5 | 11.80 | -: NEWTON - OJO | ATHLETICS MPUMALANGA |
| 6 | 11.80 | -: OOSTHUIZEN - SIAS | LIMPOPO ATHLETICS |
| 7 | 12.12 | -: MSANE - LWANDLE | ATHLETICS MPUMALANGA |