| Place | Performance | Athlete | Team |
| 1 | 11.05 | Q: PIENAAR - FRANCO | NORTH WEST MAINSTREAM |
| 2 | 11.12 | Q: RATHEBE - OMPHILE | GAUTENG MAINSTREAM |
| 3 | 11.14 | Q: THOMAS - AKIEL | KWAZULU NATAL MAINSTREAM |
| 4 | 11.18 | -: DU PLESSIS - ETHAN | EASTERN CAPE MAINSTREAM |
| 5 | 11.42 | -: MONAWA - KEGOMODITSWE | LIMPOPO MAINSTREAM |
| 6 | 11.64 | -: KEKANE - MOHALE THUTO | FREE STATE MAINSTREAM |