| Place | Performance | Athlete | Team |
| 1 | 11.27 | Q: OLIVIER - ANDRE | NORTH WEST MAINSTREAM |
| 2 | 11.36 | Q: MLENGA - ANDILE | FREE STATE MAINSTREAM |
| 3 | 11.37 | Q: MODISE - SANDILE | GAUTENG MAINSTREAM |
| 4 | 11.56 | q: MANCOTYWA - SIPHOSETHU | EASTERN CAPE MAINSTREAM |
| 5 | 11.59 | q: REDDY - TEEVIR | KWAZULU NATAL MAINSTREAM |
| 6 | 11.68 | -: CORNELSON - MUSAHDIQ | WESTERN CAPE MAINSTREAM |
| 7 | 11.86 | -: NETSHITANGANI - UNARINE | LIMPOPO MAINSTREAM |
| 8 | 12.07 | -: CARROL - LEATHAN | NORTHERN CAPE MAINSTREAM |